The race to create a real-life tricorder
In an old office building at NASA's Ames Research Center in Mountain
View, California, there's a room stacked high with plastic containers of
synthetic urine. Researchers dip small white paddles into the liquid,
wait for a grid of squares to change colors, and snap a photo with a
custom smartphone app.
It's all part of a futuristic self-diagnosis kit from startup Scanadu, which is competing to be the future of DIY health care.
Scanadu is one of 10 teams taking part in the Qualcomm Tricorder X Prize
contest to create an affordable, handheld device that consumers can use
to diagnose their medical conditions at home. The goal is to make a
working version of "Star Trek's" tricorder, the television show's
fictional diagnostic device. In the series, the ship's doctor would wave
the portable black box over a patent's body and immediately know if a
person had broken bones, a disease or if they were going to die.
The real-life tricorder
must weigh less than 5 pounds, monitor five vital signs and detect 15
medical conditions. It should let people measure their own blood
pressure, heart rate, temperature, oxygen saturation and respiratory
rate. Each system will be able to diagnose common health conditions
including diabetes, anemia, sleep apnea and pneumonia.
"We're asking teams to
put together an aggregation of technologies that's never been done
before," said Dr. Erik Viirre, the technical and medical director for
the Tricorder X Prize. "We're spurring things to market faster, better
and cheaper."
The multiyear contest is
run by X Prize, a nonprofit organization that attempts to accelerate
major technological advances. Last week, the judges narrowed down the
field of 41 teams to 10, which now have until April to create working
prototypes for consumer tests. The three groups that make the most
successful tricorders will split a $10 million prize.
In 2005, Walter De
Brouwer's 5-year-old son jumped out of a window and fell 36 feet to the
ground. After a year in emergency rooms, operating rooms and the ICU, De
Brouwer had a whole new perspective on hospitals. He saw firsthand how
powerless patients often were. Inspired by the less invasive medical
devices from science fiction, he moved to Silicon Valley and started
Scanadu.
" 'Star Trek' was not TV, it was a business plan," said 57-year-old De Brouwer.
Scanadu is already close
to having working prototypes of its tricorder system. In addition to the
Scanaflo (a single-use urine test) the company has created the Scanadu
Scout, a palm-sized disc you press to your forehead or temple for 10
seconds to take vital signs, including blood pressure, temperature,
heart and respiratory rate.
The readings are
imported to a smartphone, analyzed and tracked over time. De Brouwer's
vision is to have a constant collection of data that creates a baseline
for each user. That information will allow the Scanadu app to detect
issues early, even before there are noticeable symptoms.
These types of devices
are not meant to replace doctors, but to fill in when in-person medical
care is not available, affordable or necessary.
Every day, Dr. Basil
Harris sees patients who have waited too long to seek treatment, often
because they lack insurance or a primary care giver. There's a steady
stream of them at the Chicago emergency room where he works, showing up
days after the first symptoms of serious illnesses.
Harris, who also has a Ph.D. in engineering, leads the Tricorder X Prize finalist team Final Frontier Medical Devices.
His tricorder combines a regular tablet computer with a separate
Bluetooth gadget that takes vitals and runs other tests. The companion
tablet app walks the patient through the same types of questions Harris
asks every patient who comes into his ER.
"It does everything you
would expect a normal physician to do," said Harris. "What an ER doctor
does is make diagnoses. Doing that is somewhat an art and somewhat
science."
His team is also working
on a novel approach to a neurological exam. Using the tablet, they can
test users' vision, picking up on subtle defects caused by illness. For
example, if a person has suffered from a hemorrhagic stroke, they might
lose some vision on just one side. The tests could detect the issue and
tell the person to seek medical help immediately, cutting down on the
chance of permanent disability.
Inventing a new medical
device is only the first step to getting it into the hands of real
people. Perhaps even more useful than the money is how the X Prize is
working with the Food and Drug Administration. Getting regulatory
compliance for a new product is notoriously difficult and expensive, and
it requires clinical trials. But the FDA is working closely with the X
Prize organization.
The X Prize will also
manage the vigorous final tests that determine which devices will win.
Each team must produce 30 working prototypes of their tricorders for
consumer testers. They'll be used and reviewed by people who have one of
the conditions the tricorders are required to detect.
The final teams hail
from six countries. They include doctors, engineers, undergrads,
entrepreneurs and researchers, and all have unique approaches to the
technology. Many, like Scanadu, Final Frontier and Slovenian team MESI
Simplifying Diagnostics, are creating small gadgets that work with
existing mobile devices. Some are taking a more traditional approach
with things like blood pressure cuffs and finger pricks. The Danvantri team from India is working on a low-cost device worn around the neck specifically for developing countries.
One thing they all agree on is that this technology's time is now.
"This device, whether
it's mine or someone else's, is coming," said Harris. "It puts the
information in the hands of the consumer where they can make actionable
decisions. It really levels the playing field."
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